Chromosome-level genome assembly of Cnidium monnieri, a highly demanded traditional Chinese medicine.

Resource Type: 
Publication
Publication Type: 
Journal Article
Title: 
Chromosome-level genome assembly of Cnidium monnieri, a highly demanded traditional Chinese medicine.
Authors: 
Wang Z, He J, Qi Q, Wang K, Tang H, Feng Y, Zhao X, Yi S, Zhao Y, Xu D
Series Name: 
Scientific data
Journal Abbreviation: 
Sci Data
Volume: 
11
Issue: 
1
Page Numbers: 
667
Publication Year: 
2024
Publication Date: 
2024 Jun 22
DOI: 
10.1038/s41597-024-03523-6
ISSN: 
2052-4463
EISSN: 
2052-4463
Cross Reference: 
PMIDLoading content
Citation: 
Wang Z, He J, Qi Q, Wang K, Tang H, Feng Y, Zhao X, Yi S, Zhao Y, Xu D. Chromosome-level genome assembly of Cnidium monnieri, a highly demanded traditional Chinese medicine.. Scientific data. 2024 Jun 22; 11(1):667.
Abstract: 

Cnidium monnieri, a medicinal herb of the Cnidium genus and the Apiaceae family, is among the most important traditional Chinese medicines and is widely distributed in China. However, to date, no C. monnieri-related genomic information has been described. In this study, we assembled the C. monnieri genome of approximately 1210.23 Mb with a contig N50 of 83.14 Mb. Using PacBio HiFi and Hi-C sequencing data, we successfully anchored 93.86% of the assembled sequences to 10 pseudochromosomes (2n = 20). We predicted a total of 37,460 protein-coding genes, with 97.02% of them being functionally annotated in Non-Redundant, Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and other databases. In addition, we identified 2,778 tRNAs, 4,180 rRNAs, 258 miRNAs, and 1,700 snRNAs in the genome. This is the first reported C. monnieri genome. Hopefully, the availability of this chromosome-level reference genome provides a significant basis for upcoming natural product-related biosynthetic pathway assessment in C. monnieri.

Publication Model: 
Electronic
Language: 
English
Language Abbr: 
eng
Journal Country: 
England
PII: 
667